CN Patent

CN116077462B — 阿瑞匹坦微丸及其制备方法和包含它的制剂

Assigned to Beijing Nuokangda Pharmaceutical Technology Co ltd · Expires 2025-05-16 · 1y expired

What this patent protects

本发明涉及医药领域，具体涉及阿瑞匹坦微丸及其制备方法和包含它的制剂。阿瑞匹坦微丸从内向外依次包括空白丸芯和中间层；所述中间层含有药物和第一辅料；所述药物为阿瑞匹坦和/或阿瑞匹坦的药学上可接受的盐；所述药物的平均粒径为230‑370nm。本发明更加详细地控制了原料药的粒度，添加高级脂肪醇硫酸酯类的表面活性剂，保证了产品的生物利用度；同时可保证稳定性考察期间的溶出曲线不发生变化，保证了产品良好的稳定性。

USPTO Abstract

本发明涉及医药领域，具体涉及阿瑞匹坦微丸及其制备方法和包含它的制剂。阿瑞匹坦微丸从内向外依次包括空白丸芯和中间层；所述中间层含有药物和第一辅料；所述药物为阿瑞匹坦和/或阿瑞匹坦的药学上可接受的盐；所述药物的平均粒径为230‑370nm。本发明更加详细地控制了原料药的粒度，添加高级脂肪醇硫酸酯类的表面活性剂，保证了产品的生物利用度；同时可保证稳定性考察期间的溶出曲线不发生变化，保证了产品良好的稳定性。

Drugs covered by this patent

Patent Metadata

Patent number
CN116077462B
Jurisdiction
CN
Classification
—
Expires
2025-05-16
Drug substance claim
No
Drug product claim
No
Assignee
Beijing Nuokangda Pharmaceutical Technology Co ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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