CN Patent

CN115925603B — 索吡溴铵的制备方法

Assigned to Shandong Qidu Pharmaceutical Co Ltd · Expires 2025-07-22 · 1y expired

What this patent protects

本发明属于药物合成技术领域，具体涉及一种索吡溴铵的制备方法。所述的索吡溴铵的制备方法，包括以下步骤：制备得到(R)‑α‑环戊基扁桃酸；制备(R)‑α‑环戊基扁桃酸‑(R)‑1‑甲基‑3‑吡咯烷醇配合物；制备粗品索吡溴铵；对粗品进行精制，得到索吡溴铵；利用柱层析对索吡溴铵分离纯化，得到高纯度A‑1与A‑2。本发明提供一种索吡溴铵的制备方法，步骤简单，避免了毒性溶剂的使用，降低环境污染的同时提高了收率，适合于工业化生产，具有较高的经济效益和现实意义。

USPTO Abstract

本发明属于药物合成技术领域，具体涉及一种索吡溴铵的制备方法。所述的索吡溴铵的制备方法，包括以下步骤：制备得到(R)‑α‑环戊基扁桃酸；制备(R)‑α‑环戊基扁桃酸‑(R)‑1‑甲基‑3‑吡咯烷醇配合物；制备粗品索吡溴铵；对粗品进行精制，得到索吡溴铵；利用柱层析对索吡溴铵分离纯化，得到高纯度A‑1与A‑2。本发明提供一种索吡溴铵的制备方法，步骤简单，避免了毒性溶剂的使用，降低环境污染的同时提高了收率，适合于工业化生产，具有较高的经济效益和现实意义。

Drugs covered by this patent

Patent Metadata

Patent number
CN115925603B
Jurisdiction
CN
Classification
—
Expires
2025-07-22
Drug substance claim
No
Drug product claim
No
Assignee
Shandong Qidu Pharmaceutical Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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