CN Patent

CN115521312A — Adagrasib的固体形式及其制备方法

Assigned to Shanghai Acebright Pharmaceuticals Group Co ltd · Expires 2022-12-27 · 3y expired

What this patent protects

本发明涉及一种2‑[(2S)‑4‑[7‑(8‑氯‑1‑萘基)‑2‑[[(2R)‑1‑甲基吡咯烷‑2‑基]甲氧基]‑6,8‑二氢‑5H‑吡啶并[3,4‑d]嘧啶‑4‑基]‑1‑(2‑氟丙‑2‑烯酰基)哌嗪‑2‑基]乙腈(式I)的固体形式及其制备方法。所述的固体形式为式(I)化合物或其药学上可接受的盐的多晶型物或共晶，包括盐晶型或共晶XM‑1、盐晶型或共晶XM‑2、盐晶型或共晶XM‑3、盐晶型或共晶XM‑4或盐晶型或共晶XM‑5。

USPTO Abstract

本发明涉及一种2‑[(2S)‑4‑[7‑(8‑氯‑1‑萘基)‑2‑[[(2R)‑1‑甲基吡咯烷‑2‑基]甲氧基]‑6,8‑二氢‑5H‑吡啶并[3,4‑d]嘧啶‑4‑基]‑1‑(2‑氟丙‑2‑烯酰基)哌嗪‑2‑基]乙腈(式I)的固体形式及其制备方法。所述的固体形式为式(I)化合物或其药学上可接受的盐的多晶型物或共晶，包括盐晶型或共晶XM‑1、盐晶型或共晶XM‑2、盐晶型或共晶XM‑3、盐晶型或共晶XM‑4或盐晶型或共晶XM‑5。

Drugs covered by this patent

Patent Metadata

Patent number
CN115521312A
Jurisdiction
CN
Classification
—
Expires
2022-12-27
Drug substance claim
No
Drug product claim
No
Assignee
Shanghai Acebright Pharmaceuticals Group Co ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

Track this patent

Get a daily-checked alert when vulnerability score, expiry, classification, or assignee changes. Email, Slack, or Teams delivery. Pro: 50 watches, Free: 3.