CN Patent

CN115057822B — 一种普拉替尼中间体2097133-31-6的新合成方法

Assigned to Shanghai Youhebeide Pharmaceutical Technology Co ltd · Expires 2023-05-02 · 3y expired

What this patent protects

本发明涉及医药中间体有机合成技术领域，具体涉及一种普拉替尼中间体2097133‑31‑6的新合成方法，本发明的合成方法为以单乙二醇保护的1,4‑环己二酮为原料，经氰基化、羟胺加成、还原、关环、脱保护、酯化醚化、氯代反应得到目标产物。本发明提供了一条普拉替尼中间体2097133‑31‑6的新合成路线。该发明的优点是操作简单，条件温和，原料易得，安全性高，环保，制得的产品纯度好，收率高。

USPTO Abstract

本发明涉及医药中间体有机合成技术领域，具体涉及一种普拉替尼中间体2097133‑31‑6的新合成方法，本发明的合成方法为以单乙二醇保护的1,4‑环己二酮为原料，经氰基化、羟胺加成、还原、关环、脱保护、酯化醚化、氯代反应得到目标产物。本发明提供了一条普拉替尼中间体2097133‑31‑6的新合成路线。该发明的优点是操作简单，条件温和，原料易得，安全性高，环保，制得的产品纯度好，收率高。

Drugs covered by this patent

Patent Metadata

Patent number
CN115057822B
Jurisdiction
CN
Classification
—
Expires
2023-05-02
Drug substance claim
No
Drug product claim
No
Assignee
Shanghai Youhebeide Pharmaceutical Technology Co ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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