CN Patent

CN114907387B — 嘧啶并吡咯类kras抑制剂及其制备方法与应用

Assigned to Sun Yat Sen University · Expires 2023-11-10 · 3y expired

What this patent protects

本发明公开了一种嘧啶并吡咯类KRAS抑制剂及其制备方法与应用。该抑制剂是如通式(Ⅰ)所示的嘧啶并吡咯类衍生物、其立体异构体、稳定的同位素衍生物或其药学上可接受盐。该抑制剂对含KRAS G12C突变的细胞具有有效的抑制作用，因此具有较大的潜力。

USPTO Abstract

本发明公开了一种嘧啶并吡咯类KRAS抑制剂及其制备方法与应用。该抑制剂是如通式(Ⅰ)所示的嘧啶并吡咯类衍生物、其立体异构体、稳定的同位素衍生物或其药学上可接受盐。该抑制剂对含KRAS G12C突变的细胞具有有效的抑制作用，因此具有较大的潜力。

Drugs covered by this patent

Patent Metadata

Patent number
CN114907387B
Jurisdiction
CN
Classification
—
Expires
2023-11-10
Drug substance claim
No
Drug product claim
No
Assignee
Sun Yat Sen University
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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