CN Patent

CN114671866A — 芳基或杂芳基并吡啶酮或嘧啶酮类衍生物及其制备方法和应用

Assigned to Suzhou Zelgen Biopharmaceutical Co Ltd · Expires 2022-06-28 · 4y expired

What this patent protects

本发明涉及芳基或杂芳基并吡啶酮或嘧啶酮类衍生物及其制备方法和应用。具体地，本发明化合物具有式(I)所示结构，本发明还公开了所述化合物的制备方法及其作为KRAS G12C 抑制剂的用途，对KRAS G12C 具有很好的选择性抑制作用且具有更好的药效学、药代动力学性能和更低的毒副作用。

USPTO Abstract

本发明涉及芳基或杂芳基并吡啶酮或嘧啶酮类衍生物及其制备方法和应用。具体地，本发明化合物具有式(I)所示结构，本发明还公开了所述化合物的制备方法及其作为KRAS G12C 抑制剂的用途，对KRAS G12C 具有很好的选择性抑制作用且具有更好的药效学、药代动力学性能和更低的毒副作用。

Drugs covered by this patent

Patent Metadata

Patent number
CN114671866A
Jurisdiction
CN
Classification
—
Expires
2022-06-28
Drug substance claim
No
Drug product claim
No
Assignee
Suzhou Zelgen Biopharmaceutical Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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