CN Patent

CN114644642B — 一种噻吩并吡啶化合物的晶型a、制备方法及其药物组合物

Assigned to Shenzhen Neptunus Pharmaceutical Research Institute Co Ltd · Expires 2023-05-12 · 3y expired

What this patent protects

本发明公开了化合物2‑(4‑(7‑(2‑氟‑4‑(1‑((4‑氟苯基)氨甲酰基)环丙烷‑1‑甲酰胺)苯氧基)噻吩并[3,2‑b]吡啶‑2‑基)‑1H‑吡唑基‑1‑基)乙基缬氨酸酯盐酸盐的晶型A、制备方法以及其药物组合物。该晶型的化学稳定性高、耐高温、耐高湿、溶解性好、且生物利用度高，其药物组合物具有良好的溶出度，适用于制剂的开发。该化合物的结构式如式(I)所示：

USPTO Abstract

本发明公开了化合物2‑(4‑(7‑(2‑氟‑4‑(1‑((4‑氟苯基)氨甲酰基)环丙烷‑1‑甲酰胺)苯氧基)噻吩并[3,2‑b]吡啶‑2‑基)‑1H‑吡唑基‑1‑基)乙基缬氨酸酯盐酸盐的晶型A、制备方法以及其药物组合物。该晶型的化学稳定性高、耐高温、耐高湿、溶解性好、且生物利用度高，其药物组合物具有良好的溶出度，适用于制剂的开发。该化合物的结构式如式(I)所示：

Drugs covered by this patent

Patent Metadata

Patent number
CN114644642B
Jurisdiction
CN
Classification
—
Expires
2023-05-12
Drug substance claim
No
Drug product claim
No
Assignee
Shenzhen Neptunus Pharmaceutical Research Institute Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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