CN Patent

CN114540327A — 具有增强的碳水化合物的高强度酸性α-葡糖苷酶

Assigned to Amicus Therapeutics Inc · Expires 2022-05-27 · 4y expired

What this patent protects

披露了源自CHO细胞的重组人α葡糖苷酶(rhGAA)组合物，该组合物包含更优化的聚糖组合物，该聚糖组合物由rhGAA和在复合寡糖上的低量的末端半乳糖组成，该rhGAA比常规rhGAA更高量、包含携带甘露糖‑6‑磷酸(M6P)或双‑M6P的N‑聚糖，连同低量的非磷酸化的高甘露糖聚糖。描述了包含该rhGAA的组合物以及使用方法。

USPTO Abstract

披露了源自CHO细胞的重组人α葡糖苷酶(rhGAA)组合物，该组合物包含更优化的聚糖组合物，该聚糖组合物由rhGAA和在复合寡糖上的低量的末端半乳糖组成，该rhGAA比常规rhGAA更高量、包含携带甘露糖‑6‑磷酸(M6P)或双‑M6P的N‑聚糖，连同低量的非磷酸化的高甘露糖聚糖。描述了包含该rhGAA的组合物以及使用方法。

Drugs covered by this patent

Patent Metadata

Patent number
CN114540327A
Jurisdiction
CN
Classification
—
Expires
2022-05-27
Drug substance claim
No
Drug product claim
No
Assignee
Amicus Therapeutics Inc
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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