CN Patent

CN114487192B — 地氯雷他定口服溶液中依地酸二钠的含量测定方法

Assigned to Shandong Xinhua Lukang Pharmaceutical Co ltd · Expires 2024-05-31 · 2y expired

What this patent protects

本发明公开了地氯雷他定口服溶液中依地酸二钠的含量测定方法。具体步骤为：精密称取依地酸二钠对照品，用溶剂稀释制成每1ml溶剂中约含依地酸二钠20μg的溶液，得溶液a；精密称取地氯雷他定口服溶液约0.8mg，置10ml量瓶中，加溶剂溶解并稀释至刻度，摇匀，过滤，即得溶液b；取溶液a和溶液b各20μl注入高效液相色谱仪，进行含量测定，得依地酸二钠的含量。本发明采用UPLC法，HPLC法操作简单，专属性强，重复性好，精密度高，从而更好的控制地氯雷他定口服溶液中依地酸二钠的含量。

USPTO Abstract

本发明公开了地氯雷他定口服溶液中依地酸二钠的含量测定方法。具体步骤为：精密称取依地酸二钠对照品，用溶剂稀释制成每1ml溶剂中约含依地酸二钠20μg的溶液，得溶液a；精密称取地氯雷他定口服溶液约0.8mg，置10ml量瓶中，加溶剂溶解并稀释至刻度，摇匀，过滤，即得溶液b；取溶液a和溶液b各20μl注入高效液相色谱仪，进行含量测定，得依地酸二钠的含量。本发明采用UPLC法，HPLC法操作简单，专属性强，重复性好，精密度高，从而更好的控制地氯雷他定口服溶液中依地酸二钠的含量。

Drugs covered by this patent

Patent Metadata

Patent number
CN114487192B
Jurisdiction
CN
Classification
—
Expires
2024-05-31
Drug substance claim
No
Drug product claim
No
Assignee
Shandong Xinhua Lukang Pharmaceutical Co ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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