CN Patent

CN114478345B — 一种(r)-2-(2,5-二氟苯基)吡咯烷的制备方法

Assigned to Zhonghan Qihe County Biomedical Technology Co ltd · Expires 2024-06-14 · 2y expired

What this patent protects

本发明涉及一种(R)‑2‑(2,5‑二氟苯基)吡咯烷的制备方法，本发明的方法以廉价的2,5‑二氟甲苯为原料，经氧化反应、酯化反应、亲核取代重排、全细胞生物催化高效制备(R)‑2‑(2,5‑二氟苯基)吡咯烷，本发明的方法具有原料廉价易得，各步骤均为常规反应，无昂贵试剂且环境友好，反应条件温和，操作简单，成本低，收率高，易于工业化生产的特点。

USPTO Abstract

本发明涉及一种(R)‑2‑(2,5‑二氟苯基)吡咯烷的制备方法，本发明的方法以廉价的2,5‑二氟甲苯为原料，经氧化反应、酯化反应、亲核取代重排、全细胞生物催化高效制备(R)‑2‑(2,5‑二氟苯基)吡咯烷，本发明的方法具有原料廉价易得，各步骤均为常规反应，无昂贵试剂且环境友好，反应条件温和，操作简单，成本低，收率高，易于工业化生产的特点。

Drugs covered by this patent

Patent Metadata

Patent number
CN114478345B
Jurisdiction
CN
Classification
—
Expires
2024-06-14
Drug substance claim
No
Drug product claim
No
Assignee
Zhonghan Qihe County Biomedical Technology Co ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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