CN Patent

CN114392241B — 一种利匹韦林片及其制备方法

Assigned to Anhui Biochem Bio Pharmaceutical Co ltd · Expires 2023-07-25 · 3y expired

What this patent protects

本发明提供了一种利匹韦林片及其制备方法，所述片剂包括利匹韦林颗粒4.5‑6.5份、填充剂17‑20份、崩解剂2‑5份、助流剂1.5‑3.5份，所述利匹韦林颗粒由含有利匹韦林的丸芯和颗粒外层组成。本发明所述的利匹韦林片利用真空干燥来改变利匹韦林原有物料性质，避免后续加工中微粒聚集而影响粒径分布；同时改善疏水性抗病毒剂进行改性，溶出效果好；在粘合剂中加入利匹韦林进行沸腾造粒，并通过工艺控制来改善利匹韦林颗粒的粒径、密度，有助于物料混合均匀。

USPTO Abstract

本发明提供了一种利匹韦林片及其制备方法，所述片剂包括利匹韦林颗粒4.5‑6.5份、填充剂17‑20份、崩解剂2‑5份、助流剂1.5‑3.5份，所述利匹韦林颗粒由含有利匹韦林的丸芯和颗粒外层组成。本发明所述的利匹韦林片利用真空干燥来改变利匹韦林原有物料性质，避免后续加工中微粒聚集而影响粒径分布；同时改善疏水性抗病毒剂进行改性，溶出效果好；在粘合剂中加入利匹韦林进行沸腾造粒，并通过工艺控制来改善利匹韦林颗粒的粒径、密度，有助于物料混合均匀。

Drugs covered by this patent

Patent Metadata

Patent number
CN114392241B
Jurisdiction
CN
Classification
—
Expires
2023-07-25
Drug substance claim
No
Drug product claim
No
Assignee
Anhui Biochem Bio Pharmaceutical Co ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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