CN Patent

CN114306271B — 一种仑伐替尼组合物

Assigned to CSPC Zhongqi Pharmaceutical Technology Shijiazhuang Co Ltd · Expires 2023-04-07 · 3y expired

What this patent protects

本发明提供一种仑伐替尼组合物，通过加入酸性和碱性调节剂解决了仑伐替尼遇水胶化的问题。酸性调节剂的加入降低了溶出体系的pH，进一步避免对pH具有依赖性的甲磺酸仑伐替尼溶解性下降的问题，增加了仑伐替尼的生物利用度。

USPTO Abstract

本发明提供一种仑伐替尼组合物，通过加入酸性和碱性调节剂解决了仑伐替尼遇水胶化的问题。酸性调节剂的加入降低了溶出体系的pH，进一步避免对pH具有依赖性的甲磺酸仑伐替尼溶解性下降的问题，增加了仑伐替尼的生物利用度。

Drugs covered by this patent

Patent Metadata

Patent number
CN114306271B
Jurisdiction
CN
Classification
—
Expires
2023-04-07
Drug substance claim
No
Drug product claim
No
Assignee
CSPC Zhongqi Pharmaceutical Technology Shijiazhuang Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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