CN Patent

CN114159446A — 组织蛋白酶c抑制剂在治疗肿瘤转移中的应用

Assigned to Shanghai Institute of Nutrition and Health of CAS · Expires 2022-03-11 · 4y expired

What this patent protects

本发明涉及一种组织蛋白酶C抑制剂在治疗肿瘤转移中的应用。具体地，本发明提供了一种组织蛋白酶C(CTSC)抑制剂(AZD7986)可以有效地抑制乳腺癌的肺转移、肝转移。本发明的实验结果表明，AZD7986通过降低转移早期病灶中性粒细胞的浸润和/或中性粒细胞胞外陷阱(NETs)的形成，调控肿瘤微环境，从而抑制肿瘤转移。

USPTO Abstract

本发明涉及一种组织蛋白酶C抑制剂在治疗肿瘤转移中的应用。具体地，本发明提供了一种组织蛋白酶C(CTSC)抑制剂(AZD7986)可以有效地抑制乳腺癌的肺转移、肝转移。本发明的实验结果表明，AZD7986通过降低转移早期病灶中性粒细胞的浸润和/或中性粒细胞胞外陷阱(NETs)的形成，调控肿瘤微环境，从而抑制肿瘤转移。

Drugs covered by this patent

Patent Metadata

Patent number
CN114159446A
Jurisdiction
CN
Classification
—
Expires
2022-03-11
Drug substance claim
No
Drug product claim
No
Assignee
Shanghai Institute of Nutrition and Health of CAS
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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