CN Patent

CN114149357B — 一种γ晶型培哚普利精氨酸盐的制备方法

Assigned to Jiangsu Sinobiopharma Co ltd · Expires 2024-06-25 · 2y expired

What this patent protects

本发明提出的是一种γ晶型培哚普利精氨酸盐的制备方法，将培哚普利和L‑精氨酸加入水中，搅拌溶清后过滤，将滤液与有机溶剂以滴加方式混合，滴加完毕后降至室温搅拌析晶1~2h，抽滤得滤饼，将滤饼淋洗，抽干，烘干滤饼即得γ晶型培哚普利精氨酸盐。该方法无需低温、冻干等操作对设备无特殊要求，也无需回流或加热操作，析晶温度适用范围较广，得到的产品好过滤，易分离，且质量水平较高。

USPTO Abstract

本发明提出的是一种γ晶型培哚普利精氨酸盐的制备方法，将培哚普利和L‑精氨酸加入水中，搅拌溶清后过滤，将滤液与有机溶剂以滴加方式混合，滴加完毕后降至室温搅拌析晶1~2h，抽滤得滤饼，将滤饼淋洗，抽干，烘干滤饼即得γ晶型培哚普利精氨酸盐。该方法无需低温、冻干等操作对设备无特殊要求，也无需回流或加热操作，析晶温度适用范围较广，得到的产品好过滤，易分离，且质量水平较高。

Drugs covered by this patent

Patent Metadata

Patent number
CN114149357B
Jurisdiction
CN
Classification
—
Expires
2024-06-25
Drug substance claim
No
Drug product claim
No
Assignee
Jiangsu Sinobiopharma Co ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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