CN Patent

CN114105991A — 一种伊布替尼中间体的制备方法

Assigned to Beijing Xuansheng Pharmaceutical Co Ltd · Expires 2022-03-01 · 4y expired

What this patent protects

本发明提供了伊布替尼的制备方法及其应用，通过优化投料比和反应条件，增加了中间体的纯化步骤，且采用无机碱代替有机碱作为缚酸剂，显著减少了伊布替尼合成中间体及终产品中的杂质含量，尤其是异构体杂质的含量，为保障药品质量及临床用药安全提供了有力保障。

USPTO Abstract

本发明提供了伊布替尼的制备方法及其应用，通过优化投料比和反应条件，增加了中间体的纯化步骤，且采用无机碱代替有机碱作为缚酸剂，显著减少了伊布替尼合成中间体及终产品中的杂质含量，尤其是异构体杂质的含量，为保障药品质量及临床用药安全提供了有力保障。

Drugs covered by this patent

Patent Metadata

Patent number
CN114105991A
Jurisdiction
CN
Classification
—
Expires
2022-03-01
Drug substance claim
No
Drug product claim
No
Assignee
Beijing Xuansheng Pharmaceutical Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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