CN Patent

CN113893346B — Gcs抑制剂在制备治疗可卡因成瘾的药物中的用途

Assigned to West China Hospital of Sichuan University · Expires 2022-11-18 · 3y expired

What this patent protects

本发明公开了GCS抑制剂在制备治疗可卡因成瘾的药物中的用途，属于戒毒药物领域。本发明通过实验证明，GCS抑制剂可特异性降低伏隔核脑区葡萄糖神经酰胺类鞘脂的含量，减少树突分支数和树突棘密度，有效抑制可卡因对小鼠的行为学效应(行为敏化、奖赏效应以及自主给药行为学效应)。将GCS抑制剂用于制备治疗可卡因成瘾的药物，具有良好的应用前景。

USPTO Abstract

本发明公开了GCS抑制剂在制备治疗可卡因成瘾的药物中的用途，属于戒毒药物领域。本发明通过实验证明，GCS抑制剂可特异性降低伏隔核脑区葡萄糖神经酰胺类鞘脂的含量，减少树突分支数和树突棘密度，有效抑制可卡因对小鼠的行为学效应(行为敏化、奖赏效应以及自主给药行为学效应)。将GCS抑制剂用于制备治疗可卡因成瘾的药物，具有良好的应用前景。

Drugs covered by this patent

Patent Metadata

Patent number
CN113893346B
Jurisdiction
CN
Classification
—
Expires
2022-11-18
Drug substance claim
No
Drug product claim
No
Assignee
West China Hospital of Sichuan University
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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