CN Patent

CN113476603B — 一种红细胞膜包裹的磁性纳米颗粒及其制备方法和应用

Assigned to Central South University · Expires 2022-05-20 · 4y expired

What this patent protects

本发明涉及一种红细胞膜包裹的磁性纳米颗粒及其制备方法和应用，具体为水热法制备的PEG‑Fe 3 O 4 用经靶向修饰的红细胞膜碎片挤出包裹，制备出有免疫逃避性和灵敏磁响应性的纳米颗粒红细胞膜‑PEG‑Fe 3 O 4 ，能靶向吸附对叶酸敏感的癌细胞，方便其被磁场控制或通过光热刺激杀灭癌细胞。红细胞膜‑PEG‑Fe 3 O 4 可有效靶向吸附到叶酸敏感的癌细胞膜上，赋予癌磁响应性，有利于磁场控制运动和用光热刺激杀灭。因此在靶向治疗和产业推广方面具有潜在的应用前景。

USPTO Abstract

本发明涉及一种红细胞膜包裹的磁性纳米颗粒及其制备方法和应用，具体为水热法制备的PEG‑Fe 3 O 4 用经靶向修饰的红细胞膜碎片挤出包裹，制备出有免疫逃避性和灵敏磁响应性的纳米颗粒红细胞膜‑PEG‑Fe 3 O 4 ，能靶向吸附对叶酸敏感的癌细胞，方便其被磁场控制或通过光热刺激杀灭癌细胞。红细胞膜‑PEG‑Fe 3 O 4 可有效靶向吸附到叶酸敏感的癌细胞膜上，赋予癌磁响应性，有利于磁场控制运动和用光热刺激杀灭。因此在靶向治疗和产业推广方面具有潜在的应用前景。

Drugs covered by this patent

Patent Metadata

Patent number
CN113476603B
Jurisdiction
CN
Classification
—
Expires
2022-05-20
Drug substance claim
No
Drug product claim
No
Assignee
Central South University
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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