CN Patent

CN113387882A — 一种伐度司他及其中间体的制备方法

Assigned to Dongguan Dongyangguang Generic Research And Development Co ltd · Expires 2021-09-14 · 5y expired

What this patent protects

本发明涉及一种伐度司他及其中间体的制备方法，属于药物化学领域。所述制备方法可以通过以3‑氯‑5‑(3‑氯苯基)‑2‑氰基吡啶为起始物料，经过水解反应，再经过缩合反应得到化合物所述中间体；所述中间体化合物可通过进一步反应得到vadadustat(伐度司他)；该方法路线短，原料简单易得，成本较低，反应条件较温和，适用于工业放大生产。

USPTO Abstract

本发明涉及一种伐度司他及其中间体的制备方法，属于药物化学领域。所述制备方法可以通过以3‑氯‑5‑(3‑氯苯基)‑2‑氰基吡啶为起始物料，经过水解反应，再经过缩合反应得到化合物所述中间体；所述中间体化合物可通过进一步反应得到vadadustat(伐度司他)；该方法路线短，原料简单易得，成本较低，反应条件较温和，适用于工业放大生产。

Drugs covered by this patent

Patent Metadata

Patent number
CN113387882A
Jurisdiction
CN
Classification
—
Expires
2021-09-14
Drug substance claim
No
Drug product claim
No
Assignee
Dongguan Dongyangguang Generic Research And Development Co ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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