CN Patent

CN113274508B — 一种异硫氰酸烯丙酯的cd-mof制剂、方法及应用

Assigned to Anhui University of Traditional Chinese Medicine AHUTCM · Expires 2024-04-02 · 2y expired

What this patent protects

本发明公开了一种异硫氰酸烯丙酯的CD‑MOF制剂、方法及其应用，所述制剂以γ‑CD‑MOF为载体载入异硫氰酸烯丙酯，所述制剂的制备方法包括以下步骤：选用β‑CD、γ‑CD为有机配体合成β‑CD‑MOF、γ‑CD‑MOF晶体；调节β‑CD‑MOF、γ‑CD‑MOF晶体至中性；以中性的β‑CD‑MOF、γ‑CD‑MOF为载体对异硫氰酸烯丙酯进行载药得到β‑CD‑MOF‑AITC和γ‑CD‑MOF‑AITC；所述制剂质量评价方法从粉体学性质、体外释放、细胞毒性和肺局部耐受性逐一评价，本发明的制剂可应用于制备治疗COPD的药物或试剂盒中，也可作为用于制备治疗CO…

USPTO Abstract

本发明公开了一种异硫氰酸烯丙酯的CD‑MOF制剂、方法及其应用，所述制剂以γ‑CD‑MOF为载体载入异硫氰酸烯丙酯，所述制剂的制备方法包括以下步骤：选用β‑CD、γ‑CD为有机配体合成β‑CD‑MOF、γ‑CD‑MOF晶体；调节β‑CD‑MOF、γ‑CD‑MOF晶体至中性；以中性的β‑CD‑MOF、γ‑CD‑MOF为载体对异硫氰酸烯丙酯进行载药得到β‑CD‑MOF‑AITC和γ‑CD‑MOF‑AITC；所述制剂质量评价方法从粉体学性质、体外释放、细胞毒性和肺局部耐受性逐一评价，本发明的制剂可应用于制备治疗COPD的药物或试剂盒中，也可作为用于制备治疗COPD药物制剂、医疗器械或消毒用品中。

Drugs covered by this patent

Patent Metadata

Patent number
CN113274508B
Jurisdiction
CN
Classification
—
Expires
2024-04-02
Drug substance claim
No
Drug product claim
No
Assignee
Anhui University of Traditional Chinese Medicine AHUTCM
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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