CN113092601B — 一种化妆品中倍他米松17-丙酸酯及倍他米松21-丙酸酯的检测方法
Assigned to Suzhou Drug Inspection And Testing Research Center · Expires 2022-12-20 · 3y expired
What this patent protects
本发明提供了一种化妆品中倍他米松17‑丙酸酯及倍他米松21‑丙酸酯的检测方法，采用超高效液相色谱‑二极管阵列检测器‑飞行时间质谱法进行定性确证，超高效液相色谱‑质谱法测定含量。色谱条件：色谱柱：C18色谱柱；检测器：二极管阵列检测器、四级杆‑飞行时间质谱仪；流动相：A‑0.1％甲酸溶液、B‑0.1％甲酸(甲醇‑乙腈＝1:1)；流速：0.2‑0.5mL/min；柱温：25‑40℃；进样量：0.1‑10μL；梯度洗脱程序：0‑1min，30％B；10‑10.2min，75％‑95％B；12‑12.2min，95％‑30％B；14min，30％B。本发明方法可…
USPTO Abstract
本发明提供了一种化妆品中倍他米松17‑丙酸酯及倍他米松21‑丙酸酯的检测方法，采用超高效液相色谱‑二极管阵列检测器‑飞行时间质谱法进行定性确证，超高效液相色谱‑质谱法测定含量。色谱条件：色谱柱：C18色谱柱；检测器：二极管阵列检测器、四级杆‑飞行时间质谱仪；流动相：A‑0.1％甲酸溶液、B‑0.1％甲酸(甲醇‑乙腈＝1:1)；流速：0.2‑0.5mL/min；柱温：25‑40℃；进样量：0.1‑10μL；梯度洗脱程序：0‑1min，30％B；10‑10.2min，75％‑95％B；12‑12.2min，95％‑30％B；14min，30％B。本发明方法可特异、快速地筛查并确证化妆品中倍他米松17‑丙酸酯及倍他米松21‑丙酸酯，主要适用于日用化妆品的分析。
Drugs covered by this patent
- Diprolene (BETAMETHASONE DIPROPIONATE) · Merck & Co.
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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