CN Patent

CN113045564A — 一种阿培利司的制备方法

Assigned to SHANGHAI TIANCI INTERNATIONAL PHARMACEUTICAL CO LTD · Expires 2021-06-29 · 5y expired

What this patent protects

本发明提供了一种阿培利司的制备方法。利用2‑吡咯甲酸甲酯和N,N‑羰基二咪唑为原料，经过酰胺化反应、酰胺化反应、suzuki反应、胺解反应，得到式Ⅰ化合物阿培利司。该方法反应条件温和、处理简便、环境友好、成本低，适宜工业化大生产。

USPTO Abstract

本发明提供了一种阿培利司的制备方法。利用2‑吡咯甲酸甲酯和N,N‑羰基二咪唑为原料，经过酰胺化反应、酰胺化反应、suzuki反应、胺解反应，得到式Ⅰ化合物阿培利司。该方法反应条件温和、处理简便、环境友好、成本低，适宜工业化大生产。

Drugs covered by this patent

Patent Metadata

Patent number
CN113045564A
Jurisdiction
CN
Classification
—
Expires
2021-06-29
Drug substance claim
No
Drug product claim
No
Assignee
SHANGHAI TIANCI INTERNATIONAL PHARMACEUTICAL CO LTD
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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