CN Patent

CN112759552A — 司美替尼的合成方法

Assigned to Wuhan Jiuzhou Yumin Medical Technology Co ltd · Expires 2021-05-07 · 5y expired

What this patent protects

本发明涉及一种司美替尼的合成方法。本发明创新性的采用二乙氧基甲烷作为关环反应物，将关环反应和甲基化两步反应合并在一步，不仅产率很高，减少了反应步数。本发明的合成路线经三步反应合成得到司美替尼，其合成方法的后处理均无需柱层析分离，反应产物直接析出干燥即可。

USPTO Abstract

本发明涉及一种司美替尼的合成方法。本发明创新性的采用二乙氧基甲烷作为关环反应物，将关环反应和甲基化两步反应合并在一步，不仅产率很高，减少了反应步数。本发明的合成路线经三步反应合成得到司美替尼，其合成方法的后处理均无需柱层析分离，反应产物直接析出干燥即可。

Drugs covered by this patent

Patent Metadata

Patent number
CN112759552A
Jurisdiction
CN
Classification
—
Expires
2021-05-07
Drug substance claim
No
Drug product claim
No
Assignee
Wuhan Jiuzhou Yumin Medical Technology Co ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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