CN Patent

CN112384199A — 改善罗氟司特皮肤渗透滞后时间的方法和制剂

Assigned to Arcutis Biotherapeutics Inc · Expires 2021-02-19 · 5y expired

What this patent protects

减少皮肤渗透滞后时间会改善局部给药的罗氟司特组合物的生物利用度。较短的皮肤渗透滞后时间提供更快的疾病缓解和更持续的生物利用度，因为转移到衣服或其他人的机会更少。可通过将罗氟司特组合物配制为具有4.0‑6.5的pH和/或将罗氟司特与包含鲸蜡硬脂醇、磷酸二鲸蜡酯和鲸蜡醇聚醚‑10磷酸酯的乳化剂共混物混合来减少罗氟司特的皮肤渗透滞后时间。

USPTO Abstract

减少皮肤渗透滞后时间会改善局部给药的罗氟司特组合物的生物利用度。较短的皮肤渗透滞后时间提供更快的疾病缓解和更持续的生物利用度，因为转移到衣服或其他人的机会更少。可通过将罗氟司特组合物配制为具有4.0‑6.5的pH和/或将罗氟司特与包含鲸蜡硬脂醇、磷酸二鲸蜡酯和鲸蜡醇聚醚‑10磷酸酯的乳化剂共混物混合来减少罗氟司特的皮肤渗透滞后时间。

Drugs covered by this patent

Patent Metadata

Patent number
CN112384199A
Jurisdiction
CN
Classification
—
Expires
2021-02-19
Drug substance claim
No
Drug product claim
No
Assignee
Arcutis Biotherapeutics Inc
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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