CN Patent

CN111888335A — 一种托伐普坦的药物固体制剂及制备方法

Assigned to Fu'an Pharmaceutical Group Chongqing Ceremony Pharmaceutical Development Co ltd · Expires 2020-11-06 · 6y expired

What this patent protects

本发明公开了一种包含托伐普坦的药物固体制剂及制备方法：将托伐普坦原料药通过喷雾干燥处理，转化为无定型；其特征在于控制无定型固体分散体粉末粒径D90在35‑80微米；加入乳糖、玉米淀粉、微晶纤维素、羟丙纤维素、低取代羟丙纤维素、硬脂酸镁等辅料，通过流化床制粒，得到体内溶解性好，生物利用度高的托伐普坦药物固体制剂。

USPTO Abstract

本发明公开了一种包含托伐普坦的药物固体制剂及制备方法：将托伐普坦原料药通过喷雾干燥处理，转化为无定型；其特征在于控制无定型固体分散体粉末粒径D90在35‑80微米；加入乳糖、玉米淀粉、微晶纤维素、羟丙纤维素、低取代羟丙纤维素、硬脂酸镁等辅料，通过流化床制粒，得到体内溶解性好，生物利用度高的托伐普坦药物固体制剂。

Drugs covered by this patent

Patent Metadata

Patent number
CN111888335A
Jurisdiction
CN
Classification
—
Expires
2020-11-06
Drug substance claim
No
Drug product claim
No
Assignee
Fu'an Pharmaceutical Group Chongqing Ceremony Pharmaceutical Development Co ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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