CN111718408A — 一种Setmelanotide的制备方法
Assigned to Chengdu Shengnuo Biopharm Co ltd · Expires 2020-09-29 · 6y expired
What this patent protects
本发明提供了一种制备Setmelanotide的方法,方法中采用氨基树脂为起始树脂,按Setmelanotide的氨基序列反相依次接入相应的保护氨基酸得到Setmelanotide肽树脂,Setmelanotide保护肽树脂经酸解后和再经氧化环化后获得Setmelanotide粗品,Setmelanotide粗品再经过纯化和冻干得到Setmelanotide纯品。本发明工艺操作简单,产品总收率高,适合规模化生产。
USPTO Abstract
本发明提供了一种制备Setmelanotide的方法,方法中采用氨基树脂为起始树脂,按Setmelanotide的氨基序列反相依次接入相应的保护氨基酸得到Setmelanotide肽树脂,Setmelanotide保护肽树脂经酸解后和再经氧化环化后获得Setmelanotide粗品,Setmelanotide粗品再经过纯化和冻干得到Setmelanotide纯品。本发明工艺操作简单,产品总收率高,适合规模化生产。
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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