CN Patent

CN111393243B — 一种磷手性核苷类药物的合成方法及该方法得到的药物

Assigned to Shenzhen Bao'an New Materials Research Institute · Expires 2022-12-13 · 3y expired

What this patent protects

本发明公开了一种磷手性核苷类药物的合成方法，包括以下步骤：将膦酰氯化合物与带羟基的核苷类前药在手性过渡金属催化剂催化下反应得到磷手性核苷类药物。该方法采用特定的催化剂并控制反应条件，提高了磷手性核苷类药物的产率及对映选择性，且方法简便易行，适于扩大化生产，极具推广价值。

USPTO Abstract

本发明公开了一种磷手性核苷类药物的合成方法，包括以下步骤：将膦酰氯化合物与带羟基的核苷类前药在手性过渡金属催化剂催化下反应得到磷手性核苷类药物。该方法采用特定的催化剂并控制反应条件，提高了磷手性核苷类药物的产率及对映选择性，且方法简便易行，适于扩大化生产，极具推广价值。

Drugs covered by this patent

Patent Metadata

Patent number
CN111393243B
Jurisdiction
CN
Classification
—
Expires
2022-12-13
Drug substance claim
No
Drug product claim
No
Assignee
Shenzhen Bao'an New Materials Research Institute
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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