CN Patent

CN111171017B — 基于嘧啶的衍生物及其制备方法和应用

Assigned to Tianjin University · Expires 2021-12-24 · 4y expired

What this patent protects

本发明公开基于嘧啶的衍生物及其制备方法和应用，首先得到芳胺类化合物6‑苯基‑[1,2,4]三唑[4,3‑a]吡啶‑3‑胺，然后与2,5‑二氯‑N‑(2‑(异丙基磺酰基)苯基)嘧啶‑4‑胺经催化偶联反应得到嘧啶衍生物。本发明的优点在于其制备过程简单、易操作。所制得的产物具有ALK抑制活性，可用于制备ALK抑制剂。

USPTO Abstract

本发明公开基于嘧啶的衍生物及其制备方法和应用，首先得到芳胺类化合物6‑苯基‑[1,2,4]三唑[4,3‑a]吡啶‑3‑胺，然后与2,5‑二氯‑N‑(2‑(异丙基磺酰基)苯基)嘧啶‑4‑胺经催化偶联反应得到嘧啶衍生物。本发明的优点在于其制备过程简单、易操作。所制得的产物具有ALK抑制活性，可用于制备ALK抑制剂。

Drugs covered by this patent

Patent Metadata

Patent number
CN111171017B
Jurisdiction
CN
Classification
—
Expires
2021-12-24
Drug substance claim
No
Drug product claim
No
Assignee
Tianjin University
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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