CN Patent

CN111050807B — 一种核酸、含有该核酸的组合物与缀合物及制备方法和用途

Assigned to Suzhou Ruibo Biotechnology Co ltd · Expires 2024-05-28 · 2y expired

What this patent protects

提供了一种抑制乙型肝炎病毒基因表达的siRNA，及含有该siRNA的药物组合物和缀合物。该siRNA中的每个核苷酸各自独立地为修饰或未修饰的核苷酸。该siRNA含有正义链和反义链，该正义链含有核苷酸序列A，该核苷酸序列A与SEQ ID NO:1所示的核苷酸序列长度相等，且不多于3个核苷酸差异，该反义链含有核苷酸序列B，该核苷酸序列B与SEQ ID NO:2所示的核苷酸序列长度相等，且不多于3个核苷酸差异。

USPTO Abstract

提供了一种抑制乙型肝炎病毒基因表达的siRNA，及含有该siRNA的药物组合物和缀合物。该siRNA中的每个核苷酸各自独立地为修饰或未修饰的核苷酸。该siRNA含有正义链和反义链，该正义链含有核苷酸序列A，该核苷酸序列A与SEQ ID NO:1所示的核苷酸序列长度相等，且不多于3个核苷酸差异，该反义链含有核苷酸序列B，该核苷酸序列B与SEQ ID NO:2所示的核苷酸序列长度相等，且不多于3个核苷酸差异。

Drugs covered by this patent

Patent Metadata

Patent number
CN111050807B
Jurisdiction
CN
Classification
—
Expires
2024-05-28
Drug substance claim
No
Drug product claim
No
Assignee
Suzhou Ruibo Biotechnology Co ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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