CN Patent

CN111018835B — 一种沃诺拉赞的纯化方法

Assigned to Hunan Qianjin Xiangjiang Pharmaceutical Co ltd · Expires 2022-09-20 · 4y expired

What this patent protects

本发明公开了一种沃诺拉赞的纯化方法。该方法采用一元醇、甲酰胺和水按照一定配比制备的精制溶剂，在梯度降温条件下对沃诺拉赞粗品进行纯化，可以显著去除沃诺拉赞中存在的杂质化合物I，提高沃诺拉赞纯度的同时保持较高的收率，并且该方法操作简单，条件温和，有利于后续富马酸沃诺拉赞的制备，适用于大规模产业化生产。

USPTO Abstract

本发明公开了一种沃诺拉赞的纯化方法。该方法采用一元醇、甲酰胺和水按照一定配比制备的精制溶剂，在梯度降温条件下对沃诺拉赞粗品进行纯化，可以显著去除沃诺拉赞中存在的杂质化合物I，提高沃诺拉赞纯度的同时保持较高的收率，并且该方法操作简单，条件温和，有利于后续富马酸沃诺拉赞的制备，适用于大规模产业化生产。

Drugs covered by this patent

Patent Metadata

Patent number
CN111018835B
Jurisdiction
CN
Classification
—
Expires
2022-09-20
Drug substance claim
No
Drug product claim
No
Assignee
Hunan Qianjin Xiangjiang Pharmaceutical Co ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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