CN Patent

CN110865130B — 一种盐酸奥洛他定及其有关物质的检测方法

Assigned to Beijing Hicrystal Biopharmaceutical Co ltd · Expires 2023-08-22 · 3y expired

What this patent protects

本发明涉及一种盐酸奥洛他定及其有关物质的检测方法,包括采用高效液相色谱进行检测的步骤，所述液相色谱条件为：采用辛烷基硅烷键合硅胶色谱柱；流动相A为含有0.01％～1％离子对试剂、0.3％～1％一元胺和0.001～0.1mol/L缓冲盐的水溶液，流动相B为乙腈和/或甲醇，进行梯度洗脱；所述缓冲溶液的pH值为2.5～3.5，检测波长为220nm～280nm。本发明提供的盐酸奥洛他定及其有关物质的检测方法，可以有效分离盐酸奥洛他定及其杂质，提高检测结果的准确性，降低临床用药风险。

USPTO Abstract

本发明涉及一种盐酸奥洛他定及其有关物质的检测方法,包括采用高效液相色谱进行检测的步骤，所述液相色谱条件为：采用辛烷基硅烷键合硅胶色谱柱；流动相A为含有0.01％～1％离子对试剂、0.3％～1％一元胺和0.001～0.1mol/L缓冲盐的水溶液，流动相B为乙腈和/或甲醇，进行梯度洗脱；所述缓冲溶液的pH值为2.5～3.5，检测波长为220nm～280nm。本发明提供的盐酸奥洛他定及其有关物质的检测方法，可以有效分离盐酸奥洛他定及其杂质，提高检测结果的准确性，降低临床用药风险。

Drugs covered by this patent

Patent Metadata

Patent number
CN110865130B
Jurisdiction
CN
Classification
—
Expires
2023-08-22
Drug substance claim
No
Drug product claim
No
Assignee
Beijing Hicrystal Biopharmaceutical Co ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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