CN Patent

CN110812326B — 一种辛伐他汀混悬乳剂及其制备方法和应用

Assigned to Animal Husbandry and Veterinary Branch of Heilongjiang Academy of Agricultural Sciences · Expires 2022-04-22 · 4y expired

What this patent protects

本发明公开了一种辛伐他汀混悬乳剂及其制备方法和应用，组分包括辛伐他汀、表面活性剂、乳化剂、缓释剂、抗氧化剂和防腐剂，余量为注射用水，根据辛伐他汀药学性质结合微囊制剂的制备工艺，将辛伐他汀首先制备成具有缓释功能的微囊结构，之后与其余助剂混合制备成混悬乳剂，其中表面活性剂和乳化剂使其兼具混悬剂和乳剂的优点，提高载体中辛伐他汀有效药量，肌内注射后迅速到达靶器官，靶器官有效血药浓度维持时间长，微囊结构的缓释功能延长药物半衰期，提高药物生物利用度，减少了给药次数，降低药物毒副作用，最为重要的是无抗生素药残，具有广阔的临床应用前景。

USPTO Abstract

本发明公开了一种辛伐他汀混悬乳剂及其制备方法和应用，组分包括辛伐他汀、表面活性剂、乳化剂、缓释剂、抗氧化剂和防腐剂，余量为注射用水，根据辛伐他汀药学性质结合微囊制剂的制备工艺，将辛伐他汀首先制备成具有缓释功能的微囊结构，之后与其余助剂混合制备成混悬乳剂，其中表面活性剂和乳化剂使其兼具混悬剂和乳剂的优点，提高载体中辛伐他汀有效药量，肌内注射后迅速到达靶器官，靶器官有效血药浓度维持时间长，微囊结构的缓释功能延长药物半衰期，提高药物生物利用度，减少了给药次数，降低药物毒副作用，最为重要的是无抗生素药残，具有广阔的临床应用前景。

Drugs covered by this patent

Patent Metadata

Patent number
CN110812326B
Jurisdiction
CN
Classification
—
Expires
2022-04-22
Drug substance claim
No
Drug product claim
No
Assignee
Animal Husbandry and Veterinary Branch of Heilongjiang Academy of Agricultural Sciences
Source
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Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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