CN Patent

CN110511266B — 一种小分子多肽及其用途

Assigned to Nanfang Hospital of Southern Medical University · Expires 2022-08-30 · 4y expired

What this patent protects

本发明中公开一种小分子多肽及其用途。该小分子多肽KP‑6T具有显著抑制及逆转肾脏组织纤维化和CKD进展的作用,且无明显毒副作用,因此可用于制备有效抑制CKD进展的药物。与现有技术中公开的小分子多肽KP‑6相比,KP‑6T与KP‑6均可延缓晚期UUO小鼠的肾脏纤维化进展,但是KP‑6T中仅含有11个氨基酸,肽链更短,合成更容易、造价更低、并且更容易在体内吸收分布。

USPTO Abstract

本发明中公开一种小分子多肽及其用途。该小分子多肽KP‑6T具有显著抑制及逆转肾脏组织纤维化和CKD进展的作用,且无明显毒副作用,因此可用于制备有效抑制CKD进展的药物。与现有技术中公开的小分子多肽KP‑6相比,KP‑6T与KP‑6均可延缓晚期UUO小鼠的肾脏纤维化进展,但是KP‑6T中仅含有11个氨基酸,肽链更短,合成更容易、造价更低、并且更容易在体内吸收分布。

Drugs covered by this patent

Patent Metadata

Patent number
CN110511266B
Jurisdiction
CN
Classification
Expires
2022-08-30
Drug substance claim
No
Drug product claim
No
Assignee
Nanfang Hospital of Southern Medical University
Source
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