CN Patent

CN110483551B — 一种劳拉替尼游离碱的晶体

Assigned to Beijing Saisiyuan Biomedical Technology Co ltd · Expires 2021-10-22 · 5y expired

What this patent protects

本发明公开了一种(10R)‑7‑氨基‑12‑氟‑2,10,16‑三甲基‑15‑氧代‑10,15,16,17‑四氢‑2H‑8,4‑(次甲基桥)吡唑并[4,3‑h][2,5,11]苯并氧杂二氮杂十四熳环‑3‑甲腈(劳拉替尼)游离碱的晶体，该晶体使用Cu‑Ka射线进行测定的X‑射线粉末衍射图谱中，至少包含以下特征峰：衍射角2 θ 值为7.85±0.2°、12.21±0.2°、17.16±0.2°、17.92±0.2°、20.59±0.2°和23.44±0.2°；所得的晶体稳定性好，适于工业化生产。此外，本发明还提供所述晶体的制备方法和药用组合物。

USPTO Abstract

本发明公开了一种(10R)‑7‑氨基‑12‑氟‑2,10,16‑三甲基‑15‑氧代‑10,15,16,17‑四氢‑2H‑8,4‑(次甲基桥)吡唑并[4,3‑h][2,5,11]苯并氧杂二氮杂十四熳环‑3‑甲腈(劳拉替尼)游离碱的晶体，该晶体使用Cu‑Ka射线进行测定的X‑射线粉末衍射图谱中，至少包含以下特征峰：衍射角2 θ 值为7.85±0.2°、12.21±0.2°、17.16±0.2°、17.92±0.2°、20.59±0.2°和23.44±0.2°；所得的晶体稳定性好，适于工业化生产。此外，本发明还提供所述晶体的制备方法和药用组合物。

Drugs covered by this patent

Patent Metadata

Patent number
CN110483551B
Jurisdiction
CN
Classification
—
Expires
2021-10-22
Drug substance claim
No
Drug product claim
No
Assignee
Beijing Saisiyuan Biomedical Technology Co ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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