CN Patent

CN110204552B — 一类噻吩并[3,2-d]嘧啶衍生物、其制备方法、药物组合物与用途

Assigned to Shanghai Institute of Materia Medica of CAS · Expires 2021-08-17 · 5y expired

What this patent protects

本发明提供了式1所示化合物或其药学上可接受的盐，同时提供了其制备方法及用途，本发明将免疫抑制剂，例如博马度胺或来那度胺等与Menin‑MLL1蛋白‑蛋白相互作用抑制剂以适当的连接臂结合，所得化合物显示了一定的Menin‑MLL1蛋白‑蛋白相互作用抑制活性以及较好的细胞增殖抑制活性。

USPTO Abstract

本发明提供了式1所示化合物或其药学上可接受的盐，同时提供了其制备方法及用途，本发明将免疫抑制剂，例如博马度胺或来那度胺等与Menin‑MLL1蛋白‑蛋白相互作用抑制剂以适当的连接臂结合，所得化合物显示了一定的Menin‑MLL1蛋白‑蛋白相互作用抑制活性以及较好的细胞增殖抑制活性。

Drugs covered by this patent

Patent Metadata

Patent number
CN110204552B
Jurisdiction
CN
Classification
—
Expires
2021-08-17
Drug substance claim
No
Drug product claim
No
Assignee
Shanghai Institute of Materia Medica of CAS
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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