CN Patent

CN110105327A — 一种7,8-二氟-6,11-二氢-二苯并噻吩并-11-醇的制备方法

Assigned to Nanjing Huanran Biotechnology Co Ltd · Expires 2019-08-09 · 7y expired

What this patent protects

本发明涉及一种7,8‑二氟‑6,11‑二氢‑二苯并噻吩并‑11‑醇的制备方法，具体涉及以2，3‑二氟甲苯作为原料，经过溴化反应、氰基化反应、苄溴化反应、取代反应、水解反应、环合反应、还原反应高效合成7,8‑二氟‑6,11‑二氢‑二苯并噻吩并‑11‑醇。本发明提供的巴洛沙韦中间体7,8‑二氟‑6,11‑二氢‑二苯并[B,E]噻吩并‑11‑醇的制备方法是一种高收率、低成本、环保、易操作、适宜工业化的制备方法。

USPTO Abstract

本发明涉及一种7,8‑二氟‑6,11‑二氢‑二苯并噻吩并‑11‑醇的制备方法，具体涉及以2，3‑二氟甲苯作为原料，经过溴化反应、氰基化反应、苄溴化反应、取代反应、水解反应、环合反应、还原反应高效合成7,8‑二氟‑6,11‑二氢‑二苯并噻吩并‑11‑醇。本发明提供的巴洛沙韦中间体7,8‑二氟‑6,11‑二氢‑二苯并[B,E]噻吩并‑11‑醇的制备方法是一种高收率、低成本、环保、易操作、适宜工业化的制备方法。

Drugs covered by this patent

Patent Metadata

Patent number
CN110105327A
Jurisdiction
CN
Classification
—
Expires
2019-08-09
Drug substance claim
No
Drug product claim
No
Assignee
Nanjing Huanran Biotechnology Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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