CN Patent

CN109970667A — 一种雷西纳德的精制方法

Assigned to Jiangsu Wan Biochemical Pharmaceutical Refco Group Ltd · Expires 2019-07-05 · 7y expired

What this patent protects

本发明公开了一种雷西纳德的合成精制方法，以4‑(4‑环丙基萘‑1‑基)‑1H‑1,2,4‑三唑‑5(4H)‑硫醇为起始原料，经与溴乙酸乙酯烷基化反应、与N‑溴代丁二酰亚胺溴代反应、经氢氧化钠水解、氢溴酸中和、精制、干燥，成功的合成出高纯度雷西纳德原料药成品，通过对每一步中间体、产物的纯化，从而得到符合要求的高纯度终产品，本发明所述方法易于进行产品收集，适合工业化生产。

USPTO Abstract

本发明公开了一种雷西纳德的合成精制方法，以4‑(4‑环丙基萘‑1‑基)‑1H‑1,2,4‑三唑‑5(4H)‑硫醇为起始原料，经与溴乙酸乙酯烷基化反应、与N‑溴代丁二酰亚胺溴代反应、经氢氧化钠水解、氢溴酸中和、精制、干燥，成功的合成出高纯度雷西纳德原料药成品，通过对每一步中间体、产物的纯化，从而得到符合要求的高纯度终产品，本发明所述方法易于进行产品收集，适合工业化生产。

Drugs covered by this patent

Patent Metadata

Patent number
CN109970667A
Jurisdiction
CN
Classification
—
Expires
2019-07-05
Drug substance claim
No
Drug product claim
No
Assignee
Jiangsu Wan Biochemical Pharmaceutical Refco Group Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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