CN Patent

CN109956906B — 一种噁拉戈利关键中间体的制备方法

Assigned to Aurisco Pharmaceutical Co ltd · Expires 2021-01-29 · 5y expired

What this patent protects

本发明涉及制药领域，具体涉及一种噁拉戈利关键中间体的制备方法，以简单易得的Boc‑D‑苯甘氨醇为起始原料，包含氨基化、酰胺化、芳基化偶联、环合、苄胺取代和脱保护六步反应，该合成路线起始原料简单易得，反应条件较为温和，后处理简单，避免使用了贵金属催化剂，大大降低了工艺合成成本，得到的中间体纯度和收率也很高，非常适合车间规模化生产。

USPTO Abstract

本发明涉及制药领域，具体涉及一种噁拉戈利关键中间体的制备方法，以简单易得的Boc‑D‑苯甘氨醇为起始原料，包含氨基化、酰胺化、芳基化偶联、环合、苄胺取代和脱保护六步反应，该合成路线起始原料简单易得，反应条件较为温和，后处理简单，避免使用了贵金属催化剂，大大降低了工艺合成成本，得到的中间体纯度和收率也很高，非常适合车间规模化生产。

Drugs covered by this patent

Patent Metadata

Patent number: CN109956906B
Jurisdiction: CN
Classification: —
Expires: 2021-01-29
Drug substance claim: No
Drug product claim: No
Assignee: Aurisco Pharmaceutical Co ltd
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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