CN Patent

CN109912674A — 一种坎格雷洛四钠盐的制备方法

Assigned to Yabao Pharmaceutical Group Corp · Expires 2019-06-21 · 7y expired

What this patent protects

本发明涉及一种坎格雷洛四钠盐的制备方法，以N‑[2‑(甲硫基)乙基]‑2‑[(3,3,3‑三氟丙基)硫基]腺苷为原料，经两步反应得到含坎格雷洛四钠盐的反应液，再经C18硅胶柱层析进行分离纯化一次，即得到坎格雷洛四钠盐纯品。本发明的合成路线短，反应条件温和，反应充分，操作简便，产物收率高、纯度高，环境友好，适合大规模制备。

USPTO Abstract

本发明涉及一种坎格雷洛四钠盐的制备方法，以N‑[2‑(甲硫基)乙基]‑2‑[(3,3,3‑三氟丙基)硫基]腺苷为原料，经两步反应得到含坎格雷洛四钠盐的反应液，再经C18硅胶柱层析进行分离纯化一次，即得到坎格雷洛四钠盐纯品。本发明的合成路线短，反应条件温和，反应充分，操作简便，产物收率高、纯度高，环境友好，适合大规模制备。

Drugs covered by this patent

Patent Metadata

Patent number
CN109912674A
Jurisdiction
CN
Classification
—
Expires
2019-06-21
Drug substance claim
No
Drug product claim
No
Assignee
Yabao Pharmaceutical Group Corp
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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