CN Patent

CN109232607A — 劳拉替尼的合成方法

Assigned to Shenyang Pharmaceutical University · Expires 2019-01-18 · 7y expired

What this patent protects

本发明属于医药技术领域，涉及劳拉替尼(PF‑06463922)的合成方法，即5‑氟‑3‑甲基异苯并呋喃‑1(3H)‑酮与1‑甲基‑3–((甲氨基)甲基)‑1H‑吡唑‑5‑腈经过氨解、取代、偶联、手性拆分等反应步骤最终合成劳拉替尼(PF‑06463922)，或者(S)‑5‑氟‑3‑甲基异苯并呋喃‑1(3H)‑酮与1‑甲基‑3–((甲氨基)甲基)‑1H‑吡唑‑5‑腈经过氨解、取代、偶联等反应步骤最终合称成劳拉替尼(PF‑06463922),为抗肿瘤药物劳拉替尼(PF‑06463922)的合成提供了新的方法。

USPTO Abstract

本发明属于医药技术领域，涉及劳拉替尼(PF‑06463922)的合成方法，即5‑氟‑3‑甲基异苯并呋喃‑1(3H)‑酮与1‑甲基‑3–((甲氨基)甲基)‑1H‑吡唑‑5‑腈经过氨解、取代、偶联、手性拆分等反应步骤最终合成劳拉替尼(PF‑06463922)，或者(S)‑5‑氟‑3‑甲基异苯并呋喃‑1(3H)‑酮与1‑甲基‑3–((甲氨基)甲基)‑1H‑吡唑‑5‑腈经过氨解、取代、偶联等反应步骤最终合称成劳拉替尼(PF‑06463922),为抗肿瘤药物劳拉替尼(PF‑06463922)的合成提供了新的方法。

Drugs covered by this patent

Patent Metadata

Patent number
CN109232607A
Jurisdiction
CN
Classification
—
Expires
2019-01-18
Drug substance claim
No
Drug product claim
No
Assignee
Shenyang Pharmaceutical University
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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