CN Patent

CN109195954A — 沃雷生的中间体的手性拆分及其共晶

Assigned to Nandia Co · Expires 2019-01-11 · 7y expired

What this patent protects

本发明涉及通过(R)‑5‑甲基‑1,4‑二氮杂环庚烷‑1‑羧酸苄酯盐酸盐与(R)‑(+)‑1,1,2‑三苯基‑1,2‑乙二醇((R)‑TED)形成共晶制备苏沃雷生及其药学上可接受的盐的方法。该共晶提供苏沃雷生的中间体、特别是(rac)‑5‑甲基‑1,4‑二氮杂环庚烷‑1‑羧酸苄酯或其盐酸盐的拆分。本发明还涉及可用于这种制备方法的新型共晶。

USPTO Abstract

本发明涉及通过(R)‑5‑甲基‑1,4‑二氮杂环庚烷‑1‑羧酸苄酯盐酸盐与(R)‑(+)‑1,1,2‑三苯基‑1,2‑乙二醇((R)‑TED)形成共晶制备苏沃雷生及其药学上可接受的盐的方法。该共晶提供苏沃雷生的中间体、特别是(rac)‑5‑甲基‑1,4‑二氮杂环庚烷‑1‑羧酸苄酯或其盐酸盐的拆分。本发明还涉及可用于这种制备方法的新型共晶。

Drugs covered by this patent

Patent Metadata

Patent number: CN109195954A
Jurisdiction: CN
Classification: —
Expires: 2019-01-11
Drug substance claim: No
Drug product claim: No
Assignee: Nandia Co
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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