CN Patent

CN109134356A — 一种中间体2-氨基吡啶-4-甲醇的制备方法

Assigned to Guide (suzhou) Fine Chemical Co Ltd · Expires 2019-01-04 · 7y expired

What this patent protects

本发明公开了一种中间体2‑氨基吡啶‑4‑甲醇的制备方法，包括以下步骤：以4‑甲基吡啶‑2‑甲醛为原料，经氯取代反应，将甲基转化成氯甲基；再进行氧化反应，将醛基转化为羧基，之后与三乙胺和DPPA反应，将羧基转化成氨基，最后将氯甲基氧化成为羟甲基，制得2‑氨基吡啶‑4‑甲醇。本申请的制备方法操作简单，条件温和，副产物较少，产物纯度高，产物收率较高。

USPTO Abstract

本发明公开了一种中间体2‑氨基吡啶‑4‑甲醇的制备方法，包括以下步骤：以4‑甲基吡啶‑2‑甲醛为原料，经氯取代反应，将甲基转化成氯甲基；再进行氧化反应，将醛基转化为羧基，之后与三乙胺和DPPA反应，将羧基转化成氨基，最后将氯甲基氧化成为羟甲基，制得2‑氨基吡啶‑4‑甲醇。本申请的制备方法操作简单，条件温和，副产物较少，产物纯度高，产物收率较高。

Drugs covered by this patent

Patent Metadata

Patent number
CN109134356A
Jurisdiction
CN
Classification
—
Expires
2019-01-04
Drug substance claim
No
Drug product claim
No
Assignee
Guide (suzhou) Fine Chemical Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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