CN Patent

CN108926719B — 用c(RGD-ACP-K)修饰的长循环脂质体

Assigned to Beijing Gretson Biomedical Technology Co Ltd · Expires 2020-09-01 · 6y expired

What this patent protects

本发明涉及用c(RGD‑ACP‑K)修饰的长循环脂质体。本发明属于药物制剂领域，特别是靶向药物制剂领域。更具体而言，本发明涉及一种长循环脂质体，所述脂质体的表面用c(RGD‑ACP‑K)修饰，并且所述脂质体包含多柔比星或其药学上可接受的盐例如盐酸多柔比星作为抗癌活性剂。所述长循环脂质体能将抗癌活性剂靶向递送到肿瘤新生血管内皮细胞和肿瘤细胞内，并且能延长脂质体在体内的循环时间，从而增强抗肿瘤药物的治疗效果。

USPTO Abstract

本发明涉及用c(RGD‑ACP‑K)修饰的长循环脂质体。本发明属于药物制剂领域，特别是靶向药物制剂领域。更具体而言，本发明涉及一种长循环脂质体，所述脂质体的表面用c(RGD‑ACP‑K)修饰，并且所述脂质体包含多柔比星或其药学上可接受的盐例如盐酸多柔比星作为抗癌活性剂。所述长循环脂质体能将抗癌活性剂靶向递送到肿瘤新生血管内皮细胞和肿瘤细胞内，并且能延长脂质体在体内的循环时间，从而增强抗肿瘤药物的治疗效果。

Drugs covered by this patent

Patent Metadata

Patent number
CN108926719B
Jurisdiction
CN
Classification
—
Expires
2020-09-01
Drug substance claim
No
Drug product claim
No
Assignee
Beijing Gretson Biomedical Technology Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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