CN Patent

CN108727347B — 一种阿片样物质受体(mor)激动剂的晶型及其制备方法

Assigned to Jiangsu Hengrui Medicine Co Ltd · Expires 2020-06-16 · 6y expired

What this patent protects

本发明涉及一种阿片样物质受体(MOR)激动剂的晶型及其制备方法。具体地，本发明涉及(1S,4S)‑4‑乙氧基‑N‑(2‑((R)‑9‑(吡啶‑2‑基)‑6‑氧杂螺[4.5]癸‑9‑基)乙基)‑1,2,3,4‑四氢萘‑1‑胺的A晶型及其制备方法。本发明式(I)化合物的A晶型具备良好的晶型稳定性，并且所用结晶溶剂低毒低残留，可更好地用于临床治疗。

USPTO Abstract

本发明涉及一种阿片样物质受体(MOR)激动剂的晶型及其制备方法。具体地，本发明涉及(1S,4S)‑4‑乙氧基‑N‑(2‑((R)‑9‑(吡啶‑2‑基)‑6‑氧杂螺[4.5]癸‑9‑基)乙基)‑1,2,3,4‑四氢萘‑1‑胺的A晶型及其制备方法。本发明式(I)化合物的A晶型具备良好的晶型稳定性，并且所用结晶溶剂低毒低残留，可更好地用于临床治疗。

Drugs covered by this patent

Patent Metadata

Patent number
CN108727347B
Jurisdiction
CN
Classification
—
Expires
2020-06-16
Drug substance claim
No
Drug product claim
No
Assignee
Jiangsu Hengrui Medicine Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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