CN Patent

CN108670955A — 一种雷迪帕韦固体分散体的热熔挤出制备方法

Assigned to NANJING ACESYS PHARMATECH CO Ltd · Expires 2018-10-19 · 8y expired

What this patent protects

本发明公开了一种雷迪帕韦固体分散体的热熔挤出制备方法，将雷迪帕韦和辅料按一定的比例混合，过筛后混匀，制备物理混合物，在特定温度和挤出速率下加入到热熔挤出机，经冷却、粉碎，获得固体分散体颗粒或粉末。该方法制备雷迪帕韦固体分散体对原药的稳定性影响较小，制备的固体分散体具有快速溶出的特点。

USPTO Abstract

本发明公开了一种雷迪帕韦固体分散体的热熔挤出制备方法，将雷迪帕韦和辅料按一定的比例混合，过筛后混匀，制备物理混合物，在特定温度和挤出速率下加入到热熔挤出机，经冷却、粉碎，获得固体分散体颗粒或粉末。该方法制备雷迪帕韦固体分散体对原药的稳定性影响较小，制备的固体分散体具有快速溶出的特点。

Drugs covered by this patent

Patent Metadata

Patent number: CN108670955A
Jurisdiction: CN
Classification: —
Expires: 2018-10-19
Drug substance claim: No
Drug product claim: No
Assignee: NANJING ACESYS PHARMATECH CO Ltd
Source: FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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