CN Patent

CN108658935A — 来那度胺新晶型、其制备方法及其医药用途

Assigned to Tianjin University · Expires 2018-10-16 · 8y expired

What this patent protects

本发明涉及来那度胺二水合物新晶型、其制法及其药物组合物与应用。所述二水合物晶型DH结晶度高、重现性好、无有机溶剂，无水晶型formα稳定性高、重现性好、易于控制；其制备方法为：将来那度胺用水或硝基甲烷溶解，室温混悬，离心后的固体分别于40℃和70℃干燥，即分别获得二水合物晶型DH和无水晶型formα，操作简单，易于控制。

USPTO Abstract

本发明涉及来那度胺二水合物新晶型、其制法及其药物组合物与应用。所述二水合物晶型DH结晶度高、重现性好、无有机溶剂，无水晶型formα稳定性高、重现性好、易于控制；其制备方法为：将来那度胺用水或硝基甲烷溶解，室温混悬，离心后的固体分别于40℃和70℃干燥，即分别获得二水合物晶型DH和无水晶型formα，操作简单，易于控制。

Drugs covered by this patent

Patent Metadata

Patent number
CN108658935A
Jurisdiction
CN
Classification
—
Expires
2018-10-16
Drug substance claim
No
Drug product claim
No
Assignee
Tianjin University
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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