CN Patent

CN108623561B — 一种制备哌尼诺酸化合物的方法

Assigned to Ocean University of China · Expires 2025-04-01 · 1y expired

What this patent protects

一种哌尼诺酸化合物的合成方法，以苯胺和乙氧基甲叉丙二酸已二酯为起始原料经缩合反应，Gould‑Jacob反应形成喹啉母环，再经过溴代以及铃木反应制得2‑(1‑(叔丁氧羰基)‑1 H ‑吡咯‑2‑基)‑4‑氯喹啉‑3‑甲酸乙酯中间体，最后经过水解制备得到哌尼诺酸(penicinoline)。

USPTO Abstract

一种哌尼诺酸化合物的合成方法，以苯胺和乙氧基甲叉丙二酸已二酯为起始原料经缩合反应，Gould‑Jacob反应形成喹啉母环，再经过溴代以及铃木反应制得2‑(1‑(叔丁氧羰基)‑1 H ‑吡咯‑2‑基)‑4‑氯喹啉‑3‑甲酸乙酯中间体，最后经过水解制备得到哌尼诺酸(penicinoline)。

Drugs covered by this patent

Patent Metadata

Patent number
CN108623561B
Jurisdiction
CN
Classification
—
Expires
2025-04-01
Drug substance claim
No
Drug product claim
No
Assignee
Ocean University of China
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

Track this patent

Get a daily-checked alert when vulnerability score, expiry, classification, or assignee changes. Email, Slack, or Teams delivery. Pro: 50 watches, Free: 3.