CN Patent

CN108264482A — 一种卡博替尼的制备方法

Assigned to Nanjing Fine Chemical Co Ltd · Expires 2018-07-10 · 8y expired

What this patent protects

本发明涉及一种卡博替尼的制备方法，具体涉及以5，6‑二甲氧基‑4‑羟基喹啉、TsCl、对氟硝基苯、1‑(4‑氟苯基)氨基羰基环丙烷甲羧酸为原料，经过羟基保护反应、偶联反应、还原反应、缩合反应四步合成卡博替尼；本发明提供的卡博替尼的制备方法是一种高收率、低成本、三废少、易操作、安全、适宜工业化的制备方法。

USPTO Abstract

本发明涉及一种卡博替尼的制备方法，具体涉及以5，6‑二甲氧基‑4‑羟基喹啉、TsCl、对氟硝基苯、1‑(4‑氟苯基)氨基羰基环丙烷甲羧酸为原料，经过羟基保护反应、偶联反应、还原反应、缩合反应四步合成卡博替尼；本发明提供的卡博替尼的制备方法是一种高收率、低成本、三废少、易操作、安全、适宜工业化的制备方法。

Drugs covered by this patent

Patent Metadata

Patent number
CN108264482A
Jurisdiction
CN
Classification
—
Expires
2018-07-10
Drug substance claim
No
Drug product claim
No
Assignee
Nanjing Fine Chemical Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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