CN Patent

CN108239644B — 一种小干扰核酸和药物组合物及其用途

Assigned to Suzhou Ruibo Biotechnology Co Ltd · Expires 2021-05-28 · 5y expired

What this patent protects

本公开涉及一种小干扰核酸和药物组合物及其用途，该siRNA含有互补的正义链和反义链，所述正义链含有如SEQ ID NO.24、SEQ ID NO.26、SEQ ID NO.28或SEQ ID NO.30所示的核苷酸序列，反义链含有如SEQ ID NO.25、SEQ ID NO.27、SEQ ID NO.29或SEQ ID NO.31所示的核苷酸序列；且所述siRNA的磷酸‑糖骨架中的磷酸骨架和/或核苷酸戊糖上具有或不具有修饰基团。本公开提供了全新高效的siRNA及其药物组合物，可以有效预防和/或治疗血脂异常。

USPTO Abstract

本公开涉及一种小干扰核酸和药物组合物及其用途，该siRNA含有互补的正义链和反义链，所述正义链含有如SEQ ID NO.24、SEQ ID NO.26、SEQ ID NO.28或SEQ ID NO.30所示的核苷酸序列，反义链含有如SEQ ID NO.25、SEQ ID NO.27、SEQ ID NO.29或SEQ ID NO.31所示的核苷酸序列；且所述siRNA的磷酸‑糖骨架中的磷酸骨架和/或核苷酸戊糖上具有或不具有修饰基团。本公开提供了全新高效的siRNA及其药物组合物，可以有效预防和/或治疗血脂异常。

Drugs covered by this patent

Patent Metadata

Patent number
CN108239644B
Jurisdiction
CN
Classification
—
Expires
2021-05-28
Drug substance claim
No
Drug product claim
No
Assignee
Suzhou Ruibo Biotechnology Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

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