CN107879964B — 1-(5-(2-氟苯基)-1-(3-(3-甲氧丙氧基)苯磺酰氯)-1h-吡咯-3-基)-n-甲基胺的制备方法
Assigned to Jiangsu Carephar Pharmaceutical Co ltd · Expires 2023-02-10 · 3y expired
What this patent protects
本发明在现有的基础上，提供了一种1‑(5‑(2‑氟苯基)‑1‑3‑(3‑甲氧丙氧基)苯磺酰氯)‑1H‑吡咯‑3‑基)‑N‑甲基胺的制备方法，由3‑(3‑甲氧基丙氧基)苯磺酰氯经过磺酰胺化、还原胺化等反应步骤得到1‑(5‑(2‑氟苯基)‑1‑3‑(3‑甲氧丙氧基)苯磺酰氯)‑1H‑吡咯‑3‑基)‑N‑甲基胺。该制备方法反应周期短，避免高毒性试剂，简化处理操作。是一种大规模、高效率、低成本得到1‑(5‑(2‑氟苯基)‑1‑3‑(3‑甲氧丙氧基)苯磺酰氯)‑1H‑吡咯‑3‑基)‑N‑甲基胺的制备方法。
USPTO Abstract
本发明在现有的基础上，提供了一种1‑(5‑(2‑氟苯基)‑1‑3‑(3‑甲氧丙氧基)苯磺酰氯)‑1H‑吡咯‑3‑基)‑N‑甲基胺的制备方法，由3‑(3‑甲氧基丙氧基)苯磺酰氯经过磺酰胺化、还原胺化等反应步骤得到1‑(5‑(2‑氟苯基)‑1‑3‑(3‑甲氧丙氧基)苯磺酰氯)‑1H‑吡咯‑3‑基)‑N‑甲基胺。该制备方法反应周期短，避免高毒性试剂，简化处理操作。是一种大规模、高效率、低成本得到1‑(5‑(2‑氟苯基)‑1‑3‑(3‑甲氧丙氧基)苯磺酰氯)‑1H‑吡咯‑3‑基)‑N‑甲基胺的制备方法。
Drugs covered by this patent
Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.
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