CN Patent

CN107698500A — 一种奈妥匹坦的制备方法

Assigned to Sichuan Haiway Pharmaceutical Co Ltd · Expires 2018-02-16 · 8y expired

What this patent protects

本发明公开了一种奈妥匹坦的制备方法，属于医药化合物领域。本发明将2‑氯‑5氨基吡啶与甲酸缩合，然后经还原、Boc保护、碘代，然后经偶联、脱保护后与2‑(3,5‑双三氟甲基‑苯基)‑2‑甲基丙酸缩合，最后与N‑甲基哌嗪取代后得到奈妥匹坦。本发明提供的制备工艺各步骤副反应少，收率高，后处理简单，对环境污染小，得到产品纯度高，单杂低。

USPTO Abstract

本发明公开了一种奈妥匹坦的制备方法，属于医药化合物领域。本发明将2‑氯‑5氨基吡啶与甲酸缩合，然后经还原、Boc保护、碘代，然后经偶联、脱保护后与2‑(3,5‑双三氟甲基‑苯基)‑2‑甲基丙酸缩合，最后与N‑甲基哌嗪取代后得到奈妥匹坦。本发明提供的制备工艺各步骤副反应少，收率高，后处理简单，对环境污染小，得到产品纯度高，单杂低。

Drugs covered by this patent

Patent Metadata

Patent number
CN107698500A
Jurisdiction
CN
Classification
—
Expires
2018-02-16
Drug substance claim
No
Drug product claim
No
Assignee
Sichuan Haiway Pharmaceutical Co Ltd
Source
FDA Orange Book + USPTO grounding via Google Patents

Bibliographic data sourced from FDA Orange Book + USPTO public records. Plain-English summary generated by AI grounded in source text. Patent term extensions (PTR, SPC, pediatric) may shift the effective expiry. Not legal advice.

Track this patent

Get a daily-checked alert when vulnerability score, expiry, classification, or assignee changes. Email, Slack, or Teams delivery. Pro: 50 watches, Free: 3.